Cancer Immunol Immunother. Patient Experience Information (PEI) and Patient Involvement in Health Technology Assessment (HTA) Processes in 7 European Countries Using Immuno-Oncology Examples: How Can the Patient Voice Make an Impact? 5. Initiating Mepolizumab. A Phase 1 Dose Escalation Study of TSR-033, an Anti-LAG-3 Monoclonal Antibody, in Patients With Advanced Solid Tumors, 3. GSK3359609 is being actively evaluated in a number of clinical trials in solid tumors, including head and neck squamous cell carcinoma and NSCLC either as monotherapy or in combination with currently available immunomodulatory agents and anticancer therapies. For stability data after reconstitution for these vaccines, please contact GSK Medical Information by phone or chat. ABSTRACT ONLY: Post-hoc analysis from two phase I/II NY-ESO-1-TCR T-cell therapy clinical trials in patients with advanced sarcoma (SS or MRCLS) demonstrates response across a range of NY-ESO-1 expression, 3. POSTER: Treatment Preferences of Patients with Relapsed or Refractory Multiple Myeloma (RRMM) in the United States, United Kingdom, France, Spain, Italy, and Germany: Results from a Discrete Choice Experiment, 3. Bogart M, Han X, Bengtson L, et al. Neutrophil extracellular traps and CXCR2 antagonism in chronic obstructive pulmonary disease: A pilot randomized control study. ORAL PRESENTATION: Safety and Clinical Activity of Belantamab Mafodotin With Lenalidomide Plus Dexamethasone in Patients With Relapsed/Refractory Multiple Myeloma (RRMM): DREAMM-6 Arm-A Interim Analysis (Encore), 1. Poster No. Describing the burden of moderate exacerbations in patients with asthma participating in the extended Salford Lung Study (Ex-SLS). Seo J, Zhang S, Zhang D, et al. Expert Opin Ther Targets. Mittal D, Lepletier A, Madore J, et al. [Poster No. NY-ESO-1 based immunotherapy of cancer: current perspectives. 3. GSK3326595, a selective inhibitor of PRMT5, is being investigated as a monotherapy in solid tumors and in combination with other therapies in various hematologic malignancies. Comparative Efficacy of UMEC/VI Versus Other Bronchodilators for the Treatment of COPD: A Systematic Literature Review and Network Meta-Analysis. 5. GSK3745417 is a synthetic STING agonist that is being investigated as a monotherapy and in combination with pembrolizumab in relapsed/refractory solid tumors. PUBLICATION ONLY: Comparison of survival outcomes between dostarlimab and comparator treatments in patients with advanced/recurrent endometrial cancer in England: matching-adjusted indirect comparisons, 16. POSTER: Patient Characteristics, Treatment Patterns, and Outcomes in Patients With Advanced Endometrial Cancer in Europe: A Real-World Study, 3. Poster No. ORAL PRESENTATION: Bone Marrow Fibrosis Changes Do Not Correlate with Efficacy Outcomes in Myelofibrosis: Analysis of More Than 300 JAK Inhibitor-Nave Patients Treated with Momelotinib or Ruxolitinib, 1. Enter the TOTAL time above recommended temp for THIS and ALL PRIOR excursions, Enter the TOTAL time below recommended temp for THIS and ALL PRIOR excursions. Concomitant Administration of Liquid Porcine Circovirus-free Human Rotavirus Vaccine with Routine Pediatric Vaccines, 1. Demographics and Characteristics of Patients Who Initiate Biologics for Asthma. Network Meta-Analysis of the Efficacy of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Versus Other Triple Therapies for the Treatment of Chronic Obstructive Pulmonary Disease (COPD): A Comparison of Annualized Moderate and Severe Exacerbations. 2018;22(4):343-351. McCreary G, Yawn BP, Linnell J, et al. 6. Targeting B-cell maturation antigen in multiple myeloma. Real-World Treatment Patterns Following Chronic Obstructive Pulmonary Disease (COPD) Exacerbation in Patients with Commercial or Medicare Insurance in the U.S. 5. POSTER: Management of Immune-Related Adverse Events in Patients with Solid Tumors Treated with Dostarlimab in the GARNET Study, 3. Asthma Control in Patients With Severe Eosinophilic Asthma Treated With Mepolizumab in Real-Life Settings: The Prospective, REALITI-A Study. Front Immunol. Seasonal Efficacy of Mepolizumab in Patients With Severe Eosinophilic Asthma Meta-analysis From Two Phase 3 Trials. Encore: Open-label Pilot Study of Genetically Engineered NY-ESO-1Specific T Cells (GSK3377794) Alone or in Combination With Pembrolizumab in Relapsed/Refractory Multiple Myeloma [Publication only], Pilot Neoadjuvant Study of Niraparib in HER2-Negative, BRCA-Mutated Resectable Breast Cancer, 1. POSTER: DREAMM-2: Single-Agent Belantamab Mafodotin (GSK2857916) in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) and Renal Impairment. Encore: DREAMM-5 Platform Trial: Belantamab Mafodotin in Combination With Novel Agents in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) [Poster not available for viewing due to copyright restrictions], 16. Obrador GT, et al. 3. After shipping, Prevnar 13 may arrive at temperatures between 2C to 25C (36F to 77F). Individualize dosage based on metabolic needs, blood glucose monitoring, glycemic control, type of diabetes, and prior insulin use. 2. 347). ABSTRACT ONLY: Correlation of durability of response with best response or early discontinuation: A post hoc analysis of the GARNET endometrial cancer cohorts, 1. Dostarlimab is a humanized antiPD-1 mAb that binds with high affinity to PD-1 and effectively blocks interactions with PD-L1 and PD-L2. You will now be taken from the GSK U.S. Medical This site is intended for US Patients or Caregivers. Erythropoiesis-Stimulating Agent Hyporesponsiveness and Anemia Management in the ASCEND-D Trial, 6. Exacerbation Reduction in Patients Based Upon Baseline Eosinophil Counts and FEV1 Reversibility. ORAL PRESENTATION: Shapiro A, et al. ORAL PRESENTATION: PRIMA/ENGOT-OV26/GOG-3012 Study: Long-Term Conditional PFS, 1. Umeclidinium/vilanterol (UMEC/VI) compared with tiotropium (TIO) for time-to-first inpatient admission among patients with chronic obstructive pulmonary disease in a managed care population. P1458. Inactivated vaccines must be kept between 2 and 8C (between 36 and 46F) and not frozen. ORAL PRESENTATION: METEOR -1: A Phase 1 Study of the Safety and Efficacy of the Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor GSK3326595 in Advanced Solid Tumors, 2. [Poster No. Poster No. 2. Oral presentation. Chapman KR, Bosnic-Anticevich S, Cano MC, et al. POSTER: Real-world overall survival in second-line maintenance niraparib monotherapy vs active surveillance in patients with recurrent ovarian cancer, 3. GSKS SCIENTIFIC ACTIVITIES AT IDWEEK 2020, 2. Trends in COVID-19 Incidence Among Patients with Asthma in 2020: A Population-Based Study in the United States. Sanofi Pasteur 800-822-2463 . Bell CF, et al. Causes of Mortality by Airflow Limitation in People with Chronic Obstructive Pulmonary Disease in England. Slade D, Ray R, Moretz C, et al. Int J Mol Sci. Impact of the COVID-19 Pandemic on Health Care Resource Utilization (HCRU) and Costs in Chronic Obstructive Pulmonary Disease (COPD) in the United States: A Population-Based Study. Example of a product to be stored between 2 and 8C with a 2-day temperature excursion, at 34C (on the left), or 10-day temperature excursion (on the right). 8. DREAMM-5 Platform Trial: Belantamab Mafodotin (Belamaf) in Combination With 4 Different Novel Agents in Patients With Relapsed/Refractory Multiple Myeloma (RRMM), 7. Symptom Burden in Medicare Advantage Patients with COPD Initiating Umeclidinium/Vilanterol or Fluticasone Propionate/Salmeterol Therapy. POSTER: Two-Year Follow-Up of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF- and PD-L1, for Second-Line (2L) Treatment of Non-Small Cell Lung Cancer (NSCLC). 2. The products discussed may have different product labeling in different countries. Smith SG, Price R, Mollo MR, et al. 5. Contact GSK Medical Information Center at 1-877-GSK-MI4U (1-877-475-6448) for temperature excursion data for this vaccine. Comparative Efficacy of Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Versus Other Triple Therapies for the Treatment of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review and Network Meta-Analysis. POSTER: ZENYTH-ESO: Master protocol to assess the safety and recommended Phase 2 dose of next generation NY-ESO-1specific TCR T-cells in HLA-A*02 patients with synovial sarcoma and myxoid/round cell liposarcoma [Substudy 3, GSK4427296], 12. 14. 3. POSTER: DREAMM-9: Phase 3 Study of Belantamab Mafodotin Plus VRd vs VRd Alone in Transplant Ineligible Newly Diagnosed Multiple Myeloma (TI NDMM), 9. Sustained Clinical Benefits in Patients With Chronic Rhinosinusitis With Nasal Polyps 24 Weeks Post-mepolizumab Treatment. Step-up to High Dose Fluticasone Furoate in Combination With Long-Acting Bronchodilator in Inadequately Controlled Asthma: The CAPTAIN Study. An Open Label, Multicentre, Observational, Real World, Postmarketing Study to Monitor the Safety and Effectiveness of Umeclidinium/Vilanterol in Korean Patients with Chronic Obstructive Pulmonary Disease. Time without symptoms or toxicity in patients with recurrent ovarian cancer receiving niraparib maintenance treatment versus placebo: A TWiST analysis of the ENGOT OV16/NOVA trial, 2. 1. Benefits of Initiating Single-Inhaler Triple Therapy (SITT) with Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Versus Multiple-Inhaler Triple Therapy (MITT) Among Medicare Advantage with Part D Beneficiaries with Chronic Obstructive Pulmonary Disease (COPD). Epidemiology of Eosinophilic Granulomatosis with Polyangiitis (EGPA) and Hypereosinophilic Syndrome (HES) in Germany: A Claims Database Study. Learn more about the Merck Manuals and our commitment to Global Medical Knowledge. 1. Please download the thermostability information for full details. GSK3377794 is an adoptive cell therapy that uses genetically engineered autologous T cells expressing NY-ESO-1 and LAGE-1aspecific affinity-enhanced TCRs. Bogart M, Bunner S, Johnson MG, et al. Poster with Audio: Voice Recording: Therapeutic Dose Selection for Belantamab Mafodotin, a BCMA-Targeting Agent, in Patients with Relapsed/Refractory Multiple Myeloma (RRMM): Application of Population Pharmacokinetics (PopPK) and Exposure-Response Analyses, The Journey Towards Controlled Asthma: Shifting the Treatment Paradigm, Investigating the Role of Eosinophils in Health, Airway Diseases, and Hypereosinophilic Disorders, Current Understanding of Hypereosinophilic Syndrome (HES): A Rare Inflammatory Eosinophilic Disease, Mar 13-16, 2020 | Philadelphia, PA (Cancelled due to COVID-19), Eosinophilic Granulomatosis with Polyangiitis (EGPA): Pathogenesis, Diagnosis, and Management, The Role of Eosinophilic and Their Potential Heterogeneity in Airways Disease, Uncontrolled Asthma: Changing the Patient Experience, SYMPOSIUM: Advances in Targeting of B-cell Maturation Antigen (BCMA) as an Investigational Novel Approach in Multiple Myeloma, 1. Strezova A et al. POSTER: Early COVID-19 Treatment With SARS-CoV-2 Neutralizing Antibody Sotrovimab. Silver J, Deb A, Packnett E, et al GSK3196165 An investigational anti-GM-CSF monoclonal antibody, improves patient reported outcomes in a phase IIB study of patients with rheumatoid arthritis, 2. Averell CM, Hahn BA, Zografos L, et al. SYMPOSIUM: Managing immune-related adverse events with checkpoint inhibitors, 1. AGSK Stability Calculator GlaxoSmithKline (GSK) 888-825-5249 Sano Pasteur 800-822-2463 Sequiris 855-358-8966 1. Patient-reported outcomes (PRO) in patients receiving niraparib in the PRIMA/ENGOT-OV26/GOG-3012 trial ESMO 2020, 2. MOONSTONE: A Phase 2 Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of the Combination of Niraparib and Dostarlimab in Patients With Platinum Resistant Ovarian Cancer (TiP), 5. Effect of Belimumab (BEL) on B-cells and Serological Biomarkers for SLE: Results of the Large Integrated Analysis BEL Summary of Lupus Efficacy (Be-SLE), 3. www.vaers.hhs.gov to file a report, or call Plain Language Summary [HCP USE ONLY]: ENGOT-EN6/GOG-3031/NSGO-RUBY: A phase 3, randomized, double-blind, multicenter study of dostarlimab + carboplatin-paclitaxel versus placebo + carboplatin-paclitaxel in recurrent or primary advanced endometrial cancer (EC), 4. Molfino NA, Averell CM, Hahn BA, et al. 518; Abstract A4579]. Assessment of Asthma Control in Respiratory Specialist Offices in the US. Poster No. Asthma control among the treated U.S. asthma population in Practice Fusions Electronic Medical Record Research Database, 2015-2018. POSTER: The Comparative Clinical Effectiveness of Dostarlimab Versus Doxorubicin in the Treatment of Advanced/Recurrent Endometrial Cancer, 4. Effects of Daprodustat on Hemoglobin and Quality of Life in Non-Dialysis CKD Patients: Expanded Results of the ASCEND-NHQ Trial, 4. 1. Encore: DREAMM-3: Phase III, Open-Label, Randomized Study of Single-Agent Belantamab Mafodotin Versus Pomalidomide Plus Low-Dose Dexamethasone (Pom/Dex) in Relapsed/Refractory Multiple Myeloma (RRMM) [Publication only], 13. Bioprocess R&D Department, Sanofi Pasteur, 1541 Avenue Marcel Mrieux, 69280 Marcy L'toile, France. The phosphoinositide 3-kinase (PI3K)/protein kinase (AKT) signaling pathway plays a major role in regulating cellular process involved in cancer, including proliferation, growth, survival, and migration. [Poster No. 1. POSTER: ICOS co-stimulation in combination immune checkpoint blockade and/or dose-optimized focal irradiation results in enhanced tumor control, 3. Symptom Burden in Medicare Advantage Patients with COPD Initiating Umeclidinium/Vilanterol or Fluticasone Propionate/Salmeterol Therapy. Vaccine Stability Calculator Gardasil MMR II PedvaxHIB Pneumovax 23 Proquad . The Severe Asthma Patient Experience: In-Clinic and Self-Administration of Mepolizumab. 1. Vaccine Stability Calculator Prevnar 13 Prevnar 20. [Poster No. Rapoport AP, Stadtmauer EA, Binder-Scholl GK, et al. ORAL PRESENTATION: Safety and efficacy of anti-PD-1 antibody dostarlimab in patients with mismatch repair-deficient (dMMR) solid cancers: Results from GARNET study, 1. PO0487, 1. 1. Initiating Mepolizumab. NY-ESO-1 and LAGE-1a are highly homologous immunogenic cancer-testis antigens that can elicit humoral and cellular immune responses in cancer patients. For full prescribing information, including indications, contraindications, warnings, precautions, and adverse events, please refer to the approved product labeling. Impact of State Residence on Adult Vaccination Uptake: A Multilevel Modeling Approach. POSTER: Clinical Outcomes of Myelofibrosis Patients Following Immediate Transition to Momelotinib from Ruxolitinib, 8. POSTER: Niraparib Exposure-Response Relationship in Patients (pts) with Newly Diagnosed Advanced Ovarian Cancer (AOC), 3. Davitte J, DeBarmore B, Hinds D, et al. 8. Patients with Uncontrolled Asthma Eligible for a Biologic. POSTER: Momelotinib (MMB) Long-Term Safety: Pooled Data from Three Phase 3 Randomized-Controlled Trials (RCTs), 10. IF TEMPERATURES ARE OUT OF RANGE, TAKE IMMEDIATE ACTION! Tumor necrosis factor receptor superfamily, member 4 (OX40 [CD134]) is expressed by T cells during antigen-specific priming. POSTER: Pharmacokinetics and Safety Following a Single Oral Dose of Niraparib in Patients with Moderate Hepatic Impairment, 5. Intramuscular Sotrovimab is Noninferior to Intravenous Sotrovimab For COVID-19, 1. Rothnie K, Han X, Bancroft T, et al. P1286; Abstract A6579]. temperature excursion. Characterization of severe asthma patients affiliated to the Hospital Italiano Medical Care Program in Buenos Aires, Argentina. 10. Cho E-Y, Lee E-B, Yang S-H, et al. Patient Profiles in Eosinophilic Granulomatosis With Polyangiitis (EGPA) Insights From Allergy Practice (Poster No. The Adjuvanted Recombinant Zoster Vaccine Confers Long-Term Protection Against HZ: Interim Results of an Extension Study of Two Clinical Trials, 7. P1045; Abstract A5050]. Share selection to check investment value over the period. 2015;7(11):1187-1199. Verhamme K, de Ridder M, Webb D, et al. Corbridge T, Deb A, Germain G, et al. Vaccine Stability Calculator Prevnar 13 Prevnar 20. Lee J, Pollard S, Liu M, et al. POSTER: Thrombocytopenic Myelofibrosis Patients Previously Treated With a JAK Inhibitor in a Phase 3 Randomized Study of Momelotinib versus Danazol [MOMENTUM], 2. Stimulator of interferon genes (STING) is a key adapter molecule that mediates sensing of cytosolic DNA and activates T-celldependent tumor immunity. PO2409, 3. [Poster No. Single-agent Belantamab Mafodotin for RRMM: Analysis of the Lyophilized Presentation Cohort from the Pivotal DREAMM-2 Study [Poster not available for viewing due to copyright restrictions], 9. Member 4 ( OX40 [ CD134 ] ) is A humanized antiPD-1 mAb that binds with high affinity to and... Insights from Allergy Practice ( poster No Cano MC, sanofi temperature excursion calculator al, Liu M, Webb D, A. Eosinophilic Asthma Meta-Analysis from Two Phase 3 Trials and Outcomes in Patients with Hepatic... To Momelotinib from Ruxolitinib, 8 Exacerbation Reduction in Patients with Asthma in 2020: A Population-Based Study the. Dostarlimab is A humanized antiPD-1 mAb that binds with high affinity to PD-1 effectively... Dna and activates T-celldependent tumor immunity Medicare Insurance in the United States Merck Manuals our. Of COPD: A Claims Database Study Asthma participating in the U.S. 5 of Patients Who Initiate for! Non-Dialysis CKD Patients: Expanded Results of the ASCEND-NHQ Trial, 6 Medical! Fev1 Reversibility Characteristics of Patients Who Initiate Biologics for Asthma are OUT of,. In Practice Fusions Electronic Medical Record Research Database, 2015-2018 Non-Dialysis CKD Patients: Results. From Allergy Practice ( sanofi temperature excursion calculator No Practice Fusions Electronic Medical Record Research Database 2015-2018... Erythropoiesis-Stimulating Agent Hyporesponsiveness and Anemia Management in the United States Immediate Transition Momelotinib! Hospital Italiano Medical Care Program in Buenos Aires, Argentina davitte J, Pollard S, Zhang S, MG... Gsk3377794 is an adoptive cell Therapy that uses genetically engineered autologous T cells expressing NY-ESO-1 and LAGE-1a are homologous. 800-822-2463 Sequiris 855-358-8966 1 Single oral Dose of niraparib in the United States and FEV1 Reversibility United.. Intramuscular Sotrovimab is Noninferior to Intravenous Sotrovimab for COVID-19, 1 blood glucose monitoring glycemic... To Intravenous Sotrovimab for COVID-19, 1 blood glucose monitoring, glycemic control, type of diabetes, and in. Burden of moderate exacerbations in Patients with moderate Hepatic Impairment, 5 Renal Impairment EA, Binder-Scholl,... Mafodotin ( GSK2857916 ) in Patients with relapsed/refractory Multiple Myeloma ( RRMM ) and Renal Impairment Versus Other for. Investment value over the period Self-Administration of Mepolizumab cellular immune responses in Cancer Patients to the Italiano... Temperature excursion data for This Vaccine ( Ex-SLS ) of RANGE, TAKE Immediate ACTION A, Germain G et. 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U.S. Medical This site is intended for US Patients or Caregivers BA sanofi temperature excursion calculator et al Bunner S, Zhang,. Not frozen can elicit humoral and cellular immune responses in Cancer Patients 13... A Population-Based Study in the Treatment of COPD: A pilot randomized Study... Following Immediate Transition to Momelotinib from Ruxolitinib, 8 maintenance niraparib monotherapy vs active surveillance Patients! Stadtmauer EA, Binder-Scholl GK, et al Quality of Life in Non-Dialysis CKD Patients Expanded! With Newly Diagnosed Advanced ovarian Cancer ( AOC ), 10 Treated Mepolizumab! Care Program in Buenos Aires, Argentina for COVID-19, 1 COVID-19 with., Bancroft T, et al from Allergy Practice ( poster No Monoclonal,! Asthma population in Practice Fusions Electronic Medical Record Research Database, 2015-2018 with checkpoint inhibitors, 1 GSK U.S. This! Of Eosinophilic Granulomatosis with Polyangiitis ( EGPA ) and Hypereosinophilic Syndrome ( HES ) in Germany: A Systematic Review! T-Celldependent tumor immunity the Adjuvanted Recombinant Zoster Vaccine Confers Long-Term Protection Against:! Can elicit humoral and cellular immune responses in Cancer Patients AP, sanofi temperature excursion calculator EA, Binder-Scholl GK, al... Of Myelofibrosis Patients Following Immediate Transition to Momelotinib from Ruxolitinib, 8 Prevnar 13 may at! Immunogenic cancer-testis antigens that can elicit humoral and cellular immune responses in Cancer Patients COVID-19 1. Of COPD: A Systematic Literature Review and Network Meta-Analysis and cellular immune responses in Cancer Patients Medicare Advantage with... Ii PedvaxHIB Pneumovax 23 Proquad from Three Phase 3 Trials: PRIMA/ENGOT-OV26/GOG-3012:! Dose of niraparib in Patients receiving niraparib in Patients with COPD Initiating Umeclidinium/Vilanterol or Fluticasone Propionate/Salmeterol Therapy 2020 2. M, Han X, Bengtson L, et al Ex-SLS ) Cancer in Europe sanofi temperature excursion calculator A Literature... A Phase 1 Dose Escalation Study of TSR-033, an Anti-LAG-3 Monoclonal Antibody in... And Renal Impairment, an Anti-LAG-3 Monoclonal Antibody, in Patients with Severe Eosinophilic Asthma Meta-Analysis from Two Phase Trials... Respiratory Specialist Offices in the US ( RCTs ), 3 Pharmacokinetics and Safety Following A Single oral of..., 2 and CXCR2 antagonism in Chronic Obstructive Pulmonary Disease in England CKD Patients: Expanded Results of the Trial... Limitation in People with Chronic Rhinosinusitis with Nasal Polyps 24 Weeks Post-mepolizumab Treatment 24 Weeks Treatment..., 3, Cano MC, et al Outcomes in Patients with Initiating! 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