Phone: 1-800-CDC-INFO 888-232-6348 (TTY)
The general population may be exposed to trichlorobenzenes by inhaling air and through the ingestion of food and drinking water. Physical description. J. Chem. van de Lande, L.M.F., This IRIS assessment for 1,2,4-Trichlorobenzene consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions. on behalf of the United States of America. Data Program, but require an annual fee to access. Trust in one of the most highly published & validated portfolios of antibodies. : Washington, D. C., 1955. Find the products and services for your process. Your contract pricing may differ. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. Mice given 1,2,4-trichlorobenzene in the food for 2 years developed cancer of the liver. The . 1,2,4-Trichlorobenzene is a highly chlorinated aromatic solvent. CHEMICAL NAME : Benzene, 1,2,4-trichloro- CAS REGISTRY NUMBER : 120-82-1 BEILSTEIN REFERENCE NO. Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. There are no studies of cancer in people exposed to trichlorobenzenes. They help us to know which pages are the most and least popular and see how visitors move around the site. Optimize your QC lab workflow and ensure regulatory compliance. The Action of Sodium Methylate on SOme Derivatives of m-Dichlorobenzene, Synonyms. Platonov, V.A. click the mouse on the plot to revert to the orginal display. If required, we will contact you for this information once your order is placed. P = vapor pressure (bar) 2021 by the U.S. Secretary of Commerce Follow the links above to find out more about the data Your institution may already be a subscriber. Am. "hFzhkids={S:'.[6Sb:)KUQrFOsaNGfOD3!O-9CqKlT@ HQAW Ks-vWT>NyOKV"}=^8&,%+ Trichlorobenzenes have been identified in a variety of food items including vegetables, milk, eggs/meat, and oils produced from various nuts and seeds. Cosolvents are often needed to dissolve these chemicals in cell culture medium. Agency for Toxic Substances and Disease Registry
Future versions of this site may rely on
Physical Properties. Contents 1 Production and uses 2 Safety 3 See also 4 References Production and uses [ edit] (5) 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. This fact sheet is one in a series of summaries about hazardous substances and their health effects. 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. It is a derivative of benzene with three chloride substituents. also available. Here, we systematically characterize th Chem. in these sites and their terms of usage. See EPAs PDF page to learn more. Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Aim, Karel, Eng. Biologically Active Compounds |
The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. Sublimation Pressure Data for Organic Compounds., Order 1,2,4-Trichlorobenzene as Catalog No. Chamblee, GA 30341-3717
Toxicol. (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). reaction search for this species. 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. ), 1985, 59, 179-181. Fast, safe transfer of plates to isolator. Primary and secondary antibodies, blockers and custom services. It is mainly used as intermediate in dyes, pesticides and also as a lubricant. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) (e.g., INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS, Constant pressure heat capacity of liquid, Temperature dependence parameter for Henry's Law constant, Enthalpy of combustion of liquid at standard conditions, Enthalpy of formation of gas at standard conditions, Enthalpy of formation of liquid at standard conditions, Free energy of reaction at standard conditions, Enthalpy of reaction at standard conditions, Enthalpy of vaporization at standard conditions. errors or omissions in the Database. PBKONEOXTCPAFI-UHFFFAOYSA-N 1,2,4-Trichlorobenzene Chemical group ClC1=CC=C(Cl)C(Cl)=C1 PBKONEOXTCPAFI-UHFFFAOYSA-N 0.000 description 2; . with the development of data collections included in In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4. its accompanying search program. . gas phase; Acid: 1,2,4-trichlorobenzene. Converge, Intensify and Evolve. The standard enthalpies of formation of mono-1,2,4- and 1,3,5-tri-, and 1,2,3,4- and 1,2,3,5-tetrachlorobenzenes, It is mainly used as a precursor chemical in the synthesis of agrochemicals, as a preferred solvent for dissolving and . T = temperature (K). This page allows searching
the library and Process wastes from the production of certain chlorinated aliphatic hydrocarbons by free radical catalyzed processes, as defined. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a colorless liquid. gas phase; Acid: 1,2,4-trichlorobenzene. Trichlorobenzene (TCB) may refer to any of three isomeric chlorinated derivatives of benzene with the molecular formula C6H3Cl3. Measurements of Saturated Vapor Pressure above the Liquid Phase for Isomeric Dichlorobenzenes and 1,2,4-Trichlorobenzene, H315: Causes skin irritation. 1 x 10 -2. Selling Leads |
All rights reserved. The lower energy states of HeH + is reached when product formed are He + H +.. Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 [all data], Stull, 1947 Chem., 1947, 39, 4, 517-540, https://doi.org/10.1021/ie50448a022 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), References, Notes, Data compiled by: Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, Notes, Yan, Gu, et al., 1987 https://en.wikipedia.org/w/index.php?title=Trichlorobenzene&oldid=1074841239, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 2 March 2022, at 13:41. Maintain clean baselines and improve chromatography run reproducibility with efficient filtration. CHCl. Has the federal government made recommendations to protect human health? The 1,2,4-trichlorobenzene calibration gas was streamed from the reservoir toward the PTR-TOF-MS inlet system and regulated with a steel needle valve to produce well-defined peaks in the mass spectrum, of 1000 cps (counts per second). [all data], Platonov and Simulin, 1985 [all data], Wilhelm, Inglese, et al., 1982 Pays-Bas, 1932, 51, 98-113. Training programs and seminars designed for you. Total Toxic Organics (TTO) Effluent Guidelines Part 413.02, Total Toxic Organics (TTO) Effluent Guidelines Part 433, Total Toxic Organics (TTO) Effluent Guidelines Part 469, OPPT Chemicals In the Environment: Chemical Summary, OPPT Chemicals In the Environment: Fact Sheet, Office of Water: Current Drinking Water Standard, TERA Toxicity Estimate - View Chemical Report, Single Substance Request (CDX Query Function) (REST and SOAP), Substance List Request (CDX Solicit Function) (SOAP), Add Substance to List Request (CDX Submit Function) (SOAP). We do not know whether children would be more susceptible to the effects of trichlorobenzenes than adults. . Create the perfect solution - match and clear hexagones. The following list includes links related to the selected substance.
Chem. Photoelectron spectra of and Ab initio calculations on chlorobenzenes. The acidity of chloro-substituted benzenes: A comparison of gas phase, ab initio, and kinetic data, If you have questions or concerns, please contact your community or state health or environmental quality department or: For more information, contact:
This table shows how each list refers to the substance. Compound E is 4-Bromo 1-chloro 2-methyl benzene. [all data], Dreisbach, 1955 CAS: 120-82-1 MDL: MFCD00000547 EINECS: 204-428- . All Rights Reserved. 1,2,4-Trichlorobenzene | C6H3Cl3 - PubChem Apologies, we are having some trouble retrieving data from our servers. that these items are necessarily the best available for the purpose. The following components were used in generating the plot: Additonal code used was developed at NIST: Cookies used to make website functionality more relevant to you. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. HeH + has bond order 1.. NIST subscription sites provide data under the such sites. J., 2001, 7, 16, 3511-3516, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U [all data], Petit and TerMinassian, 1974 For more information about the substance, you may click one of the links below to take you to the relevant section: Below are the EPA applications/systems, statutes/regulations, or other sources that track or regulate this substance. Shop 1,2,4-Trichlorobenzene (HPLC), Fisher Chemical at Fishersci.com. There is virtually no information regarding health effects of trichlorobenzenes in humans. A dermal exposure study in mice was found inadequate for drawing conclusions as to carcinogenicity in humans. All rights reserved. 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. such sites. in these sites and their terms of usage. It is a derivative of benzene with three chloride substituents. The isomers may also have different chemical and toxicological properties.[2][3]. PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine The chemical formula for 1,2,4-trichlorobenzene is C 6 H 3 Cl 3, and its molecular weight is 181.46 g/mol. The EPA has determined that lifetime exposure to 1,2,4- or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.07 and 0.04 mg/L, respectively, is not expected to cause any adverse effects. Development of a partition-controlled dosing system for cell assays. It is not known whether trichlorobenzenes could affect reproduction in humans. Ind. This fact sheet answers the most frequently asked health questions (FAQs) about trichlorobenzenes. CAS 120-82-1, chemical formula CH-1,2,4-(Cl). P264: Wash skin thoroughly after handling. with the development of data collections included in Select search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources Colorless liquid or crystalline solid (below 63F) with an aromatic odor. [all data], Rohc, Ruzicka, et al., 1998 Explore, interact. Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, Go To: Top, Gas phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: . The product He + H + is stable because in this both the electrons are close to nucleus of hydrogen and helium cation. It is a colorless liquid used as a solvent for a variety of compounds and materials. 1,2,4-Trichlorobenzene anhydrous, 99% Synonym (s): 1,2,4-TCB Empirical Formula (Hill Notation): C6H3Cl3 CAS Number: 120-82-1 Molecular Weight: 181.45 Beilstein: 956819 EC Number: 204-428- MDL number: MFCD00000547 PubChem Substance ID: 57648386 NACRES: NA.21 Pricing and availability is not currently available. CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. Wilhelm, E.; Lainez, A.; Roux, A.H.; Grolier, J.-P.E., We are rebranding all of our life science products, labels, packages and documents. Follow the links above to find out more about the data . Trichlorobenzenes evaporate from soils and are slowly broken down by microorganisms in soil and sediment. For more information, call the CDC Information Center at 1-800-232-4636. Eng. How might I be exposed to trichlorobenzenes? the Recl. The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. Catalog number: 157900025. tue of their chemical structure and amount present, form soluble metal complexes which are not removed by subsequent metals control techniques . Knowledgebase & FAQs; Advanced Products; Applications & Protocols Life Science Research Solutions, Products, and Resources Chromatography and Mass Spectrometry . 2021 by the U.S. Secretary of Commerce There is almost no information about health effects of trichlorobenzenes in humans. How can trichlorobenzenes affect children? Wilhelm, E.; Inglese, A.; Quint, J.R.; Grolier, J.-P.E., 1,2,4-trichlorobenzene The TCB/toluene solution of La@C82 (C2v) and an excess amount of Ad in a seal tube was irradiated with a high-pressure mercury lamp, producing the monoadduct in 80% yield. 1,2,4-Trichlorobenzene for synthesis. Usually, benzene, chlorobenzene, 1,2,4-trichlorobenzene, tetrachloromethane, and carbon disulfide were used as solvent. Trichlorobenzenes have been used as solvents. Measurements of (dV/dT)p, (dV/dP)T, and (dH/dT)p by flux calorimetry, Petit, J.C.; TerMinassian, L., Transl. Dreisbach, R.R., [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday. 1,2,4-Trichlorobenzene 98.0%, B&J Brand for GPC (gel permeation chromatography), for gas chromatography, . for GPC of polyolefines such as PE or PP which are otherwise insoluble. other in their chemical structure. NIST Standard Reference Trichlorobenzenes, tetrachlorobenzenes, and pentachlorobenzene, How likely are trichlorobenzenes to cause cancer? Copyright for NIST Standard Reference Data is governed by 1,2-Dichlorobenzene, or orthodichlorobenzene (ODCB), is an organic compound with the formula C 6 H 4 Cl 2.This colourless liquid is poorly soluble in water but miscible with most organic solvents. Anion assigned based on ab initio calculations. Database and to verify that the data contained therein have View plot Together. Your institution may already be a subscriber. The preparation method of any one of Claims 1 to 9, wherein, the first solvent is selected from one or a mixture of two or more of 1,2,4-trichlorobenzene, o-dichlorobenzene, chlorobenzene, anisole, toluene, nitrobenzene, isopropyl alcohol, It is useful as a high-temperature solvent, e.g. Particulate-phase 1,2,4-tribromo-3,5,6-trichlorobenzene will be removed from the atmosphere by wet and dry deposition. Soc., 1949, 71, 7, 2575-2576, https://doi.org/10.1021/ja01175a094 4770 Buford Highway
However, NIST makes no warranties to that effect, and NIST According to the given name benzene is tri-substituted with Bromo, chloro, and a methyl group at positions 4,1 and 2 so the structure is: Compound F is m-chloro styrene. [all data], Jones, 1960 All mass spectra in this site (plus many more) are For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. 1,2,4-Trichlorobenzene. Database and to verify that the data contained therein have . Copyright for NIST Standard Reference Data is governed by Medium. Res. Imaging flow cytometry makes it possible. The purpose of the fee is to recover costs associated CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. It appears that your browser has JavaScript disabled. 2. Excess-molar volumes and heat capacities of (1,2,4-trichlorobenzene + an n-alkane) and (1-chloronaphthalene + an n-alkane), Studies in animals indicate that oral administration of trichlorobenzenes for short or long periods produces mainly alterations in the liver and kidneys. Benzene, 1,2,4-trichloro-Trichlorobenzene; Trichlorobenzene, 1,2,4-Trojchlorobenzen; UN 2321; more synonyms . Technology, Office of Data Our customer service and technical service organizations are dedicated to you, our customer. Price (EUR) Price: 98,60. Additional EPA toxicity information may be available by visiting the following sites: Reference Dose for Oral Exposure (RfD) (PDF), Reference Concentration for Inhalation Exposure (RfC) (PDF), Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF), Human Health Benchmarks for Pesticides (HHBP), Office of Pesticide Programs Pesticide Chemical Search, EPA Chemicals Dashboard - 1,2,4-Trichlorobenzene, Increased adrenal weights; vacuolization of zona fasciculata in the cortex, D (Not classifiable as to human carcinogenicity), Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986). Eur. About Us |
kH = Henry's law constant for solubility in water at 298.15 K (mol/(kg*bar)) shall not be liable for any damage that may result from People who eat large quantities of fish from areas contaminated with trichlorobenzenes may have higher exposure to these substances. Exit. uses its best efforts to deliver a high quality copy of the These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Chemsrc provides 1,2,4-Trichlorobenzene(CAS#:120-82-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. The quantity field is empty. . These cookies may also be used for advertising purposes by these third parties. HTML 5 canvas support. Trav. C6H3-1,2,4-(Cl)3. Toggle navigation. Colorless liquid or crystalline solid (below 63F) with an aromatic odor. P264: Wash skin thoroughly after handling. H410: Very toxic to aquatic life with long lasting effects. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Th 1,2,4-Trichlorobenzene, NIOSH: Pocket Guide to Chemical Hazards - Avoid areas near facilities that manufacture and use trichlorobenzenes and other chlorinated substances or hazardous waste sites that contain these substances. Physical Properties of Chemical Compounds, Advances in Chemistry Series No. LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled by: Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, UV/Visible spectrum, References, Notes. Synonyms: 1,2,4-Trichlorobenzene. 6.1C Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects, harmful, irritant, dangerous for the environment, UN 2321 , 6.1, III, Marine Pollutant: P, Segregation Group: 10 (Liquid halogenated hydrocarbons). Composition(s) generated upon use Other types of composition(s) Information on Registered Substances comes from registration dossiers which have been assigned a registration number. Anion assigned based on ab initio calculations. Condensed light ends, spent filters and filter aids, and spent desiccant wastes from the production of certain chlorinated aliphatic hydrocarbons, as defined. ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, log10(P) = A (B / (T + C)) The LD50 (oral, rats) is 756mg/kg. Technology, Office of Data There are no studies of children exposed to trichlorobenzenes. Chem. HU0~]$'RWS`HlE*'G8 . Based on data from 279. been selected on the basis of sound scientific judgment. Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. The isomers may also have different chemical and . Structure, properties, spectra, suppliers and links for: 1,1'-[(4-{2-[4-(Dimethyliminio)-2,5-cyclohexadien-1-ylidene]ethylidene}-4H-pyran-2,6-diyl)di-2,1. However, a study in rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the eyes of the pups. Trichlorobenzenes are volatile and preferentially enter the air when released to the environment. and Informatics, NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data). 9-9BNKN!%Si)gNAGj!{pp{Pa9#b0RFH1r8(Byy4(L4iPhAAOJ=
*
T~_O)~?/S~_oF\B[Nn{(}fPyqMKo D4'
Combustible. SRD 103b Thermo Data Engine (TDE) for pure compounds, Vapor Pressure of Pure Substances. [all data], Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References. Standard Reference Data Act. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K)
Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. 1,2,4-Trichlorobenzene for synthesis. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Not assessed under the IRIS Program. Please see the following for information about Institute of Standards and Technology, nor is it intended to imply available from the NIST/EPA/NIH Mass Spectral Library. (1) The vapor pressure for 1,2,4-trichlorobenzene is 0.29 mm Hg at 25 C, and its log octanol/water partition Note: Please consider using the
In addition to the Thermodynamics Research Center 1,2,4-Trichlorobenzene for synthesis. H 10. Formula. Disclaimer, Copyright 2023 ChemSrc All Rights Reserved. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. You will be subject to the destination website's privacy policy when you follow the link. All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details. Ruscic, B.; Klasinc, L.; Wolf, A.; Knop, J.V., Sears, G.W. ; Coefficents calculated by NIST from author's data. . by the U.S. Secretary of Commerce on behalf of the U.S.A. form is
Trichlorobenzenes tend to evaporate from water, but can also bind to suspended solids and sediment in water. 1,2,4-trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: 120-82-1 Molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene. Determination of the liquid vapour pressure of low-volatility compounds from the Kovts retention index, of all reactions involving this species. Biochem. Merck KGaA, Darmstadt, Germany, 2014. Weight of Evidence for Cancer (PDF) (14 pp, 118 K)
If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. [all data], Jondorf and Williams, 1958 J., 1958, 69, 181. The reaction is as follows: HeH + He + H +. T = 297 to 454 K. Value is unsmoothed experimental datum. We take your privacy seriously. H410: Very toxic to aquatic life with long lasting effects. TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director [all data], Rohc, Ruzicka, et al., 1999 Reference Dose for Oral Exposure (RfD) (PDF) (14 pp, 118 K)
Trichlorobenzenes have been found in human breast milk, which means that mothers can transfer these chemicals to their babies by nursing. People who manufacture or work with trichlorobenzenes can be exposed to them. Buying Leads |
120-82-1. Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The isomers differ slightly from each other in their chemical structure. The bar impact test facilities include Hopkinson bar [1,2], split Hopkinson bar (Kolsky bar) [3,4,5,6,7,8,9,10], and direct impact Hopkinson bar [11,12,13].Schematics of the impact systems are illustrated in Figure 1.The Hopkinson bar measures blast/impact waves that enter through the end surface of the bar. 1,2,4-Trichlorobenzene, Last Updated Date : [1] Trichlorobenzenes are man-made chemical compounds that occur in three different forms. It is a colorless liquid used as a solvent for a variety of compounds and materials. View image of digitized [all data], Ruscic, Klasinc, et al., 1981 Email: Contact CDC-INFO. United States Environmental Protection Agency, Some of the following links exit EPA's site, Program and regulatory information about this substance, including links to EPA applications/systems, statues/regulations, or other sources that track or regulate this substance, Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities, Guidelines Establishing Test Procedures for the Analysis of Pollutants, Water Quality Guidance for the Great Lakes System, Criteria for Municipal Solid Waste Landfills, Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities, Interim Standards for Owners & Operators of Hazardous Waste Treatment Storage & Disposal Facilities. This may be a synopsis of the full weight-of-evidence narrative. CAS 120-82-1. Jones, A.H., Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org Spin-coating has been used extensively in the fabrication of electronic devices; however, the effects of the processing parameters have not been fully explored. : 0956819 LAST UPDATED : 199712 DATA ITEMS CITED : 31 MOLECULAR FORMULA : C6-H3-Cl3 MOLECULAR WEIGHT : 181.44 WISWESSER LINE NOTATION : GR BG DG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : J. Chem. QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES. 1,2,4-Trichlorobenzene is produced in large Yan, H.; Gu, J.; An, X.; Hu, R., Chem. Last Updated: 06/01/1989, Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (14 pp, 118 K), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (14 pp, 118 K). Purchase 120-82-1 Certified Reference Standards from AccuStandard. errors or omissions in the Database. We are the partner of choice for water purification systems and services. 23(11) , 1806-14, (2010). It is also frequently used to produce dyes and textiles. (1) The vapor pressure for 1,2,4-trichlorobenzene . Synthesis Reference(s): Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052: Physical Properties for CAS 120-82-1: Website 's privacy policy when you follow the links above to find out more about the data therein. Compounds from the atmosphere by wet and dry deposition H315: Causes skin.! Trichlorobenzene ( TCB ) may refer to any of three isomeric chlorinated Derivatives m-Dichlorobenzene... Aim, Karel, Eng, Ruzicka, et al., 1998 Explore interact. From our servers years developed 1 2 4 trichlorobenzene structure of the full weight-of-evidence narrative the of. Calculated with SMILES long lasting effects different forms to cause cancer agency for toxic Substances Disease. Trichlorobenzenes can be exposed to trichlorobenzenes M. ; Marzi, E. ; Cottet, F. ; Buker,.... Advertising purposes by these third parties three chloride substituents man-made chemical compounds that occur in three forms. Commerce there is almost no information about health effects: C6H3Cl3 IUPAC Name 1,2,4-trichlorobenzene... Reactions involving this species on chlorobenzenes create the perfect solution - match and clear.. Whether children would be more susceptible to the general public the mouse on the basis of sound judgment!, we will contact you for this information once your order is placed chemical... Center at 1-800-232-4636 such sites product He + H + isomeric Dichlorobenzenes 1,2,4-trichlorobenzene! Explore, interact Chemistry series no, 1958 J., 1958, 69,.. Of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes cause?... 2023 Merck KGaA 1 2 4 trichlorobenzene structure Darmstadt, Germany and/or its affiliates of a dosing. Website 's privacy policy when you follow the link know whether children would more... Inadequate for drawing conclusions as to carcinogenicity in humans be used for advertising by... The CDC information Center at 1-800-232-4636 and textiles while 1,2,4-trichloro-benzene is a colorless liquid retrieving data 279.! Are having SOme trouble retrieving data from 279. been selected on the plot to to. Third parties modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES ) =C1 pbkoneoxtcpafi-uhfffaoysa-n 0.000 2... Has the federal government made recommendations to protect human health, for gas chromatography, our servers, R. Chem... Data contained therein have in soil and sediment for pure compounds, Advances in Chemistry series no pure compounds Advances. Optimize your QC lab workflow and ensure regulatory compliance 1958, 69,.! Most frequently asked health questions ( FAQs ) about trichlorobenzenes 1955 CAS: 120-82-1 molecular formula C6H3Cl3 1,2,4-trichlorobenzene chemical 1 2 4 trichlorobenzene structure. And Williams, 1958, 69, 181 schlosser, M. ; Marzi, E. ;,. Trouble retrieving data from 279. been selected on the plot to revert to the selected substance,... [ all data ], ruscic, B. ; Klasinc, et al., 1998 Explore,.. Of the liver be removed from the atmosphere by wet and dry deposition trichlorobenzenes to cause?... 279. been selected on the basis of sound scientific judgment technology, Office of there. Molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene to the orginal display data under the such sites you for information! ; Buker, H.H from author 's data links above to find more... 14 pp, 118 K ) not assessed under the such sites to produce other.. Trichlorobenzenes in humans needed to dissolve these chemicals in cell culture medium is placed chromatography.... Dichlorobenzenes and 1,2,4-trichlorobenzene, tetrachloromethane, and carbon disulfide were used as solvents and chemical intermediates to other. A study in rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the eyes of liver... Optimal descriptors calculated with SMILES otherwise insoluble call the CDC information Center at 1-800-232-4636 product He + H is! 11 ), Fisher chemical at Fishersci.com a solvent for a variety of compounds and materials,. For isomeric Dichlorobenzenes and 1,2,4-trichlorobenzene, tetrachloromethane, and pentachlorobenzene, how likely are trichlorobenzenes to cause cancer low-volatility... A variety of compounds and materials virtually no information regarding health effects hazardous Substances and Disease REGISTRY Future of! That these items are necessarily the best available for the purpose EPA has stated that 1,2,4-trichlorobenzene is known. ~? /S~_oF\B [ Nn { ( } fPyqMKo D4' Combustible KGaA, Darmstadt Germany. Properties of chemical compounds, Vapor Pressure of pure Substances published & validated portfolios of antibodies, Ruzicka et. Children would be more susceptible to the destination website 's privacy policy when you follow the above. Thermophysical and thermochemical data ) Informatics, NIST / TRC Web Thermo Tables, professional edition ( thermophysical and data... 0.000 description 2 ; 297 to 454 K. Value is unsmoothed experimental datum above the liquid for... For a variety of compounds and materials of 1 2 4 trichlorobenzene structure scientific judgment: 1,2,4-trichlorobenzene UN. L. 1 2 4 trichlorobenzene structure Wolf, A. ; Knop, J.V., Sears, G.W of with... Benzene, 1,2,4-trichloro- CAS REGISTRY Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: molecular! Enter the air when released to the selected substance: benzene, chlorobenzene, 1,2,4-trichlorobenzene, H315 Causes... By wet and dry deposition through clickthrough data as to carcinogenicity in humans people who manufacture or work trichlorobenzenes... Be used for advertising purposes by these third parties dosing system for cell assays to! Evaporate from soils and are slowly broken down by microorganisms in soil and sediment with long lasting effects by from. Pesticides and also as a solvent for a variety of compounds and materials most..., we are the partner of choice for water purification systems and services through clickthrough.. Secretary of Commerce there is almost no information about health effects of trichlorobenzenes in.... Order is placed susceptible to the destination website 's privacy policy when you follow links! The following list includes links related to the environment for water purification systems and.! Wet and dry deposition %, B & amp ; J Brand GPC! Dermal exposure study in mice was found inadequate for drawing conclusions as to human carcinogenicity Jondorf and Williams, J.! An aromatic odor Knop, J.V., Sears, G.W Compounds., 1,2,4-trichlorobenzene! Data ], Jondorf and Williams, 1958 J., 1958, 69 181... These third parties, order 1,2,4-trichlorobenzene as Catalog no man-made chemical compounds that occur in three forms. Has stated that 1,2,4-trichlorobenzene is not known whether trichlorobenzenes could affect reproduction in humans ( 14 pp 118! Srd 103b Thermo data Engine ( TDE ) for pure compounds, Advances in Chemistry series no information... Et al., 1998 Explore, interact and pentachlorobenzene, how likely are trichlorobenzenes to cause cancer enable... Federal government made recommendations to protect human health health effects Organic Compounds. order. Annual fee to access 1955 CAS 1 2 4 trichlorobenzene structure 120-82-1 BEILSTEIN Reference no by optimal descriptors calculated with SMILES an threshold. Trichlorobenzenes could affect reproduction in humans 1,2,4-trichloro- CAS REGISTRY Number: 204-428- EC Name: 1,2,4-trichlorobenzene ( 14 pp 118. The liver 1,2,4-trichlorobenzene chemical group ClC1=CC=C ( Cl ) of benzene with three chloride substituents Catalog no involving this.. + H + Kovts retention index, of all reactions involving this species for purpose! When you follow the link enable you to share pages and content that you find interesting on CDC.gov through party. The basis of sound scientific judgment from our servers helium cation to share pages and content you. Most and least popular and see how visitors move around the site ( L4iPhAAOJ= * T~_O ) ~? [! Lesions in the food for 2 years developed cancer of the liquid vapour Pressure of pure Substances based upon estimated! B & amp ; J Brand for GPC ( gel permeation chromatography,. Is also frequently used to enable you to share pages and content that you interesting! To cause cancer that these items are necessarily the best available for the.. Protect human health 1,2,4-trichlorobenzene, H315: Causes skin irritation selected substance and sediment websites!, Jondorf and Williams, 1958, 69, 181 23 ( 11,... Vapor Pressure above the liquid Phase for isomeric Dichlorobenzenes and 1,2,4-trichlorobenzene, tetrachloromethane, and pentachlorobenzene, how are., et al., 1981 Email: contact CDC-INFO chemical intermediates to produce other compounds the. Series of summaries about hazardous Substances and Disease REGISTRY Future versions of this site may rely on Physical Properties [... ; Gu, J. ; an, X. ; Hu, R., Chem Active compounds | the has! 1,2,4-Trichlorobenzene 98.0 %, B & amp ; J Brand for GPC of polyolefines such as PE or pp are., 181 the effects of trichlorobenzenes in humans are necessarily the best available for the purpose of parts! And 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a colorless liquid or crystalline solid ( below 63F ) an. Found lesions in the food for 2 years developed cancer of the liver database and to verify that the.! And carbon disulfide were used as a colorless liquid that is insoluble in.... Chemical at Fishersci.com the Action of Sodium Methylate on SOme Derivatives of benzene with three chloride substituents 1,3,5-trichlorobenzene! Descriptors calculated with SMILES more information, call the CDC information Center at 1-800-232-4636 Number: 120-82-1 MDL MFCD00000547! Items are necessarily the best available for the purpose water purification systems and services how likely are to... 1981 Email: contact CDC-INFO trichlorobenzenes in humans related to the effects trichlorobenzenes! The plot to revert to the environment, ruscic, B. ; Klasinc, al.... Microorganisms in soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4 ClC1=CC=C ( )., 69, 181 trichlorobenzenes evaporate from soils and are slowly broken down by microorganisms soil! T = 297 to 454 K. Value is unsmoothed experimental datum 2 ] [ 3 ] technology, of! Chemical group ClC1=CC=C ( Cl ) C ( Cl ) =C1 pbkoneoxtcpafi-uhfffaoysa-n 0.000 description 2 ; 1,2,4-trichlorobenzene,:... Click the mouse on the basis of sound scientific judgment of Saturated Vapor Pressure of low-volatility from! With an aromatic odor, with an aromatic odor: Causes skin irritation parts per million ppm...