what level of lymphocytes is dangerous

For children, it's between 3,000 and 9,500 . A count significantly higher than 3,000 lymphocytes in a microliter of blood is generally considered to be lymphocytosis in adults. All of the different types of white blood cells (WBCs)have unique functions, but they all work together when it comes to fighting diseases in our body. information and will only use or disclose that information as set forth in our notice of There are other types of white blood cells (WBCs) in our body, and one of them are called lymphocytes. Dr. Susan Leclair is a retired chancellor professor from the Department of Medical Laboratory Science at the University of Massachusetts. The treatment depends on the cause. It looks like red-brown to purple firm bumps or nodules and represents the leukemia cells depositing in the skin, Forrestel says. Grade 2: 500 - 799/mm3. Chemotherapy destroys cancer cells but also damages some healthy cells in the bone marrow. (2020). Doctors will not always recommend increasing lymphocytes. An autoimmune disorder causing ongoing (chronic) inflammation. Advertising revenue supports our not-for-profit mission. This test shows an increase in white blood cells, with higher than normal amount of lymphocytes. Although few in number, they have a vital role to play. They do this by destroying cells in the body that have been taken over by viruses or become cancerous. privacy practices. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. What Are Lymphocytes? They are also known for leaving and then re-entering the circulation many times during their entire life span. The flu or common cold may cause your lymphocyte count to dip below the lower limit. However, you may experience symptoms from whats causing the spike in your white blood cell count. Please enter your username and password to try again. Had a recent infection (most commonly viral). In this article, we look at different types of lymphocytes, what normal levels in the blood are, and what happens if levels get too low or too high. The disease often involves enlargement of lymph nodes in various parts of the body as well as enlargement of the spleen. There is no specific number of lymphocyte cells that are necessary to keep the body healthy. Chronic lymphocytic leukemia is currently more treatable than acute lymphoblastic leukemia [1] [2], but both are life threatening. What level of lymphocytes is dangerous? There are many potential causes, some of which are serious. Your FindaTopDoc account is completely free. They have both helpful and harmful effects. Having a low lymphocyte count can be acute or chronic. In some cases, low lymphocytes may signify a more serious underlying cause. This content does not have an English version. The normal range for an adult is between 1,000 and 4,800 lymphocytes per microliter (L) of blood. Doctors will first identify the underlying cause of lymphocytosis to determine the best way of lowering lymphocyte levels. If you are experiencing respiratory symptoms like coughing, congestion, and a fever, chances are you have a viral infection. The lymphocyte level can be analyzed in the blood tests. The immune system is a complex network of cells known as immune cells that include lymphocytes. Treatment for abnormal levels of lymphocytes will depend on both the cause and severity, and mild forms may not require any treatment at all. They help fight off diseases, so it's normal to see a temporary rise in the number of lymphocytes after an infection. Have a question for the experts? Contact your provider if you have a persistent infection or experience chronic (ongoing) symptoms or symptoms that get worse over time. The process of matching is similar to how a key fits into a lock. Diverse subsets of T lymphocytes influenceblood pressure. Mayo Clinic does not endorse companies or products. Low levels of lymphocytes in the blood could indicate an increased risk for death, according to a study published in CMAJ. The B and T cell screen will give an estimate of the amount of T and B cells in the blood. But they can also suppress the immune system from doing its job against certain antigens and tumors. We use cookies to ensure that we give you the best experience on our website. Many cases of lymphocytopenia are nothing to worry about and resolve with time. In: Williams Hematology. For healthy adults, the number of lymphocytes per microliter of blood should fall between 1,500 and 4,800. Stress, regardless of the origin, can temporarily compromise your immune system. Other possible causes may require medical treatment from a doctor. Easy & secure access! Lymphocytes are a type of white blood cell. Any serious infection can temporarily reduce lymphocyte . Increase your Lymphocytes (Lymphs) by 7 % to be within normal range. Kaushansky K, et al., eds. Lymphocytosis, or a high lymphocyte count, is common if youve had an infection. Some possible causes of lymphocytosis include: A doctor may perform a variety of tests to diagnose the underlying cause of lymphocytosis. For adults, a high lymphocyte count means more than 4,000 lymphocytes in 1 microliter of blood. They have the ability to respond to any type of antigen,each with a receptor capable of recognizingunique antigens. This test is called a lymphocyte subset panel. Its true that serious conditions like cancer may involve a high lymphocyte count. what does it mean when your lymphocytes are low? In addition, stress decreases the bodys lymphocytes the white blood cells that help fight off infection. If the same germ enters the body a second time, memory T cells remember it and quickly multiply, helping the body fight it more quickly. (. A normal lymphocyte range for adults is anywhere between 1,000 and 4,800 cells in 1 microliter (l) of blood. They will check an individuals symptoms and medical history. Sometimes, lymphocyte levels are elevated because of a serious condition, like leukemia. The test can help identify the percentage of lymphocytes if they contain a particular combination of a specific cell or cluster of differentiation. Lymphocyte count is one part of a complete blood count (CBC), which is a larger whole blood test. supports HTML5 video. Other acute infections such as pertussis. https://www.uptodate.com/contents/search. Here we outline more serious potential causes of lymphocytopenia. The normal range of lymphocytes varies from 800 to 5000 lymphocytes per ml of blood. Lymphocytes are a type of white blood cell. These cells work together to defend the body against foreign substances, such as bacteria, viruses, and cancer cells that can threaten its functioning. Lymphocytes: 1000 to 4000 per mm3, between 20% and 40% of total white blood cells Monocytes: 100 to 700 per mm3, between 2% and 8% of total white blood cells Eosinophils: 50 to 500 per mm3 . woman getting over a cold. Lymphocytosis (lim-foe-sie-TOE-sis), or a high lymphocyte count, is an increase in white blood cells called lymphocytes. Having a temporarily high lymphocyte count usually means that your body is working as it should to protect you from germs that make you sick. Our discussions are not a substitute for seeking medical advice or care from your own doctor. Cytomegalovirus (CMV) infection. If your doctor determines that your lymphocyte count is high, the test result might be evidence of one of the following conditions: Infection (bacterial, viral, other) Cancer of the blood or lymphatic system. There are two types of lymphocyte numbers. When we say "acute", it means something that usually occurs for a short time and gets resolved later on. Sometimes, lymphocyte levels are elevated because of a serious condition, like leukemia. High lymphocyte levels that persist may point to a more serious illness or disease, such as: viral infections, including measles, mumps, and mononucleosis. Lymphocyte counts above the normal range can be a harmless and temporary situation due to the body's normal response to an infection or inflammatoryRead . This is called immunodeficiency. If the count is too high or too low, it is a sign of an illness. People with lymphocytosis may experience symptoms depending on what is causing this spike in lymphocytes. Each antibody matches an antigen for destruction. They can be the bodys normal response to an infection, inflammatory condition, or other unusual condition, and will return to normal levels after some time. Understanding the role of lymphocytes in your body clarifies the meaning of a low lymphocyte count on your blood test. A single copy of these materials may be reprinted for noncommercial personal use only. People who have a low lymphocyte count may or may not experience any symptoms. Lymphocytes also play a role in the innate immune response, which is your bodys generalized immune response that identifies infected cells and facilitates adaptive immunity. At times, they may have fever or some other symptoms of an infection. Last medically reviewed on December 6, 2021, Neutropenia describes a significant reduction in a type of white blood cell called neutrophils. Lymphocytosis. "To understand how COVID vaccine work, it helps to first look at how our bodies fight illness . In severe cases, bone marrow transplantation and blood transfusion may be needed. Theres a much greater chance that an infection is to blame. Overview. One is in a percentage differential (%), and the other is listed as either ABS or #. A few lymphocytes enter the bloodstream while some move into the lymphatic system. Lymphocytes: 20 - 40%: 875 - 3,300: Monocytes: 2 - 9%: . The sample is dried, stained with a dye, and then dried again. A spike in your lymphocytes typically means that these white blood cells are springing into action to rid your body of an invader that can make you sick. Suppose the immune system detects a virus, bacterium, or another harmful particle, the level of lymphocytes rises. Review/update the information is beneficial, we may combine your email and website usage information with Your health care team will then prescribe medications and dietary changes to treat the underlying cause. As your body clears the infection, your lymphocytes will return to normal levels. Lymphocytosis (lim-foe-sie-TOE-sis), or a high lymphocyte count, is an increase in white blood cells called lymphocytes. But even if the level of lymphocytes in a child is elevated, this does not mean that he is terminally ill. Participate in Health Journeys in over 100 specialty communities. In monoclonal lymphocytosis, the number of lymphocytes increases due to a defect in the lymphoid cell, whereas polyclonal lymphocytosis is usually caused by an infectious or inflammatory problem. The term "chronic" means something that occurs for a longer period of time. Simple Facebook login. In these cases, lymphocytopenia will be mild, with a lymphocyte count that most likely falls just a little below the normal range. It can increase your risk of getting infections. Doctors refer to abnormally low lymphocyte numbers as lymphocytopenia. Your Lymphocytes level of 49 is a High Lymphocytes level. What is a good lymphocyte percentage? Lymphocytes can be further categorized into T lymphocytes, B lymphocytes, and natural killer cells. They play an essential role in your immune system, helping your body fight infections. Having a low lymphocyte count can be due to a number of diseases such as flu or any mild infection--those that are not serious, but at times, can put a person at a greater risk of developing other types of infections. The absolute lymphocytes count can be calculated by multiplying the total number of white blood cells against the percentage of white blood cells which are lymphocytes. This test shows if you have a higher-than-normal amount of lymphocytes. For adults, normal lymphocyte count is between 1,000 and 4,800 lymphocytes per microliter of blood. From the newly created lymphocytes cells, about 25 percent of these cells remain in the bone marrow and the rest of the 75 percent travel to the thymus and become T cells. If you are a Mayo Clinic patient, this could But if Lymphocytes levels are not in this range, you should see a doctor immediately. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Produced in bone marrow, these are an essential first. 2022 - 2023 Times Mojo - All Rights Reserved However, in some cases, the patient would have the following symptoms: There are two types of lymphocytosis: polyclonal and monoclonal. Normal values: 150,000 to 400,000 per microliter; Sidebar content. If a viral infection or bacterial infection is severe, it will compromise your immune system function and lead to low lymphocytes. A normal lymphocytes percentage is 18-45% . Does Fanconi anemia carry a risk of leukemia? People may have no symptoms, or they may have fever and other symptoms of an infection. What is the treatment for high lymphocytes? Regulatory T cells prevent any type of autoimmune diseases as well as regulate the immune system. The job of T cells is to help the body kill cancer cells and control the immune response to foreign substances. Generally speaking, however, normal lymph ranges fall between 1,000 and 4,800 lymphocytes in 1 microliter. Lymphocytes are a type of white blood cell produced in the bone marrow. Other drug hypersensitivity reactions (e.g., ethitoin, PAS, sulfasalazine, ginseng) may have an associated lymphocytosis. The condition lymphocytopenia, or lymphopenia, is characterized by abnormally low lymphocyte levels. Infants and children have more lymphocytes; less than 3,000 cells/microliter is considered to be too low in this case. Sometimes, lymphocyte levels are elevated because of a serious condition, like leukemia. Tregs control or suppress other cells in the immune system. Please remember the opinions expressed on Patient Power are not necessarily the views of our sponsors, contributors, partners or Patient Power. Common leukemia signs and symptoms include: High white blood cell count, also known as leukocytosis, can indicate a range of conditions including infections, inflammation, bodily injury and immune system disorders.Why would your doctor order a white blood cell count test? The Connection Between Platelets and Bruising, Weighing Cancer Treatment Choices at the End of Life, How to Find a CLL Specialist Outside Your Area. If lymphocyte counts remain high or low over time, they could be a sign of a health condition. All rights reserved. How to Market Your Business with Webinars? First, lets look at cases of low lymphocytes that are not necessarily a cause for concern. Lymphocytes help fight off diseases, so it's normal to see a temporary increase after an infection. Tips for Recovery from Alcoholic Fatty Liver Disease and Signs Your Liver Is Healing, Best Vegan Meal Plan for Fatty Liver Disease, High Protein Vegan Recipes You Should Try, Bariatric Surgery Diet Pre Op and Post Op: What You Should Know, New Year New Me: How to Strive for Weight Loss, What You Need to Know About High Functioning Depression and How to Manage It, Your reading falls far below the normal lower limit, Your lymphocyte levels are chronically low, Your infections result from exposure to pathogens that a healthy immune system can easily fight off, You are experiencing other chronic symptoms like unexplained weight loss and extreme fatigue, Leukemia cancers: These cancers affect the bone marrow and cause changes in red blood cells and platelets, and decrease lymphocyte levels. The values can be seen in a CBC result. The lower your lymphocyte level, the more at risk you are for viruses, including the common cold and cold sores. Lymphocytosis isn't preventable. The absolute lymphocytes count can be calculated by multiplying the total number of white blood cells against the percentage of white blood cells which are lymphocytes. Definition. Globally, inadequate intake of nutritious foods and subsequent malnutrition is a very common cause of low lymphocytes. Your doctor can determine if you have lymphocytosis during a complete medical examination. Lymphocytosis and lymphocytopenia. Infections cause a high white blood cell count because these cells are the body's way of eliminating infectious organisms viruses, bacteria, fungi, and parasites. What is a dangerous lymphocyte count? In normal situations with the absence of infections, the coarse dense nucleus of a lymphocyte is approximately the size of a red blood cell (RBC). Lymphopenia, which indicates lower levels of lymphocytes in the blood, has been tied to a higher risk of future illness and death, a new study found . Should I be concerned? The bone marrow constantly produces blood cells including lymphocytes. Monoclonal B-cell lymphocytosis and early-stage chronic lymphocytic leukemia: diagnosis, natural history, and risk stratification. Low, Normal, and High Lymphocyte How do you know when you need a blood transfusion? These T cells are then sent to circulate in the blood or placed in the peripheral tissues. Disinfect surfaces and commonly used items that may carry germs. Maybe youve been sleep deprived while you prepare for a huge presentation at work or running long distances to train for a marathon. Wash your hands frequently and thoroughly with soap and water. It is also good for people with a low B-cell count. Doctors may request a CBC if they suspect that a disease or infection is present. Coates TD. Blood circulates throughout the body, transporting substances essential to life. Interpret your laboratory results instantly with us. They maintain tolerance to germs, prevent autoimmune diseases, and limit inflammatory diseases. A high level of lymphocytes can also be a sign of lymphocytosis, which may indicate a more serious condition. For example, the Epstein-Barr virus (EPV) is one of the most common causes of abnormally high lymphocyte levels. If it is accompanied by bone marrow infiltration, it can be safely considered as a sign of CLL. Affiliate Disclosure; Contact us; Find what come to your mind; What level of lymphocytes is dangerous? If your medications are causing low lymphocytes, your doctor will monitor your lymphocyte levels and alter your treatment plan if needed. As lymphocyte counts vary with age, the diagnosis must be made using age . Lymphocyte counts above the normal range can be a harmless and temporary situation, due to the bodys normal response to an infection or inflammatory condition. (https://pubmed.ncbi.nlm.nih.gov/26065657/), Visitation, mask requirements and COVID-19 information. When there is clinical suspicion of meningitis, analysis of the CSF is mandatory. It is difficult to differentiate B and T cells through blood film viewing since they are almost identical. (4). In children, the threshold for lymphocytosis varies with age. If your levels are high, your provider may retest later to see if the spike is temporary. All lymphocytes help protect you from infection, but they have different functions. It can, but this is rare. These cells will either enter the bloodstream or move to the lymphatic system of the body. They remain in the body for decades and become memory cells, which remember antigens and help the immune system respond faster to future attacks. MS: Can the Mediterranean diet help preserve cognitive health? Most often, a temporarily high lymphocyte count is a normal effect of your body's immune system working. Lymphocytosis is defined as a peripheral blood lymphocyte count greater than 2SD above the mean for the patient population. Thats how youll get care thats most appropriate for you. Lymphocytes are an important part of the immune system. The B cells attack any invading antigens by producing antibodies, whereas the T cells destroy the cells that have become cancerous. In most cases, a high lymphocyte count shouldnt pose much of a threat since it is quite normal during and after suffering from an illness. The normal range of lymphocytes in an adult is 4,400 to 11,000 cells per microliter. Eating disorders like anorexia and bulimia deprive the body of essential nutrients for immune function, including protein, vitamin A, and vitamin D. Your doctor and a nutritionist can help determine if youre getting enough nutrients to support your immune system. The majority of T cells can live longer with an average span of 4-5 years, but can also survive for as long as 20 years. 1. https://www.merckmanuals.com/home/blood-disorders/white-blood-cell-disorders/lymphocytopenia, 2. https://www.ncbi.nlm.nih.gov/pubmed/1670632, 3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642723/, 4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185932/, 5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC464928/, 6. https://www.merckmanuals.com/home/blood-disorders/leukemias/overview-of-leukemia, 7. https://www.hindawi.com/journals/jad/2018/2036145/, Tips for Cold Prevention: How to Prevent the Common Cold, Hemochromatosis Diet: Natural Ways to Lower Iron, https://www.merckmanuals.com/home/blood-disorders/white-blood-cell-disorders/lymphocytopenia, https://www.ncbi.nlm.nih.gov/pubmed/1670632, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642723/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185932/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC464928/, https://www.merckmanuals.com/home/blood-disorders/leukemias/overview-of-leukemia, https://www.hindawi.com/journals/jad/2018/2036145/. Cytotoxic T cells are also called as "killer T cells", which can destroy cells that have been infected with antigens, cancer cells, or any other foreign cells. Your lymphocyte count is extremely low. There is a problem with They fight harmful pathogens such as bacteria and parasites, but can also, Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Once a diagnosis is established, the doctor would suggest a treatment plan based on the cause of the problem. No overall correlation between plasma Ig levels and Ig-bearing lymphocytes was found but a single infant with increased plasma IgA also showed the highest level of Ig-bearing lymphocytes among all infants. Answers ( 1) Normal lymphocyte percentage is between 20-40%. Some diseases may require long-term treatments to increase lymphocytes. The lymphocyte count may vary for both adults and children. Home | About | Contact | Copyright | Report Content | Privacy | Cookie Policy | Terms & Conditions | Sitemap. Is the ketogenic diet right for autoimmune conditions? Less often, lymphocytosis is a sign of a more serious condition. Having a low or high lymphocyte count can help identify a person's medical condition. Lymphocytes are one of the components countedin a complete blood count (CBC) test. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. A standard complete blood count (CBC) test doesnt show the levels of each type of lymphocyte. If you have low lymphocytes combined with elevated liver enzymes, this may suggest the progression of liver disease, especially if you are a heavy drinker or have a history of liver disease. On the other hand, when it starts increasing to more than 30,000 WBC/mcL, then it is called as leukocytosis (high WBC count), which is again, not a good sign. Any help please re my bloods my total white blood count is 6.8 10*9/l and my lymphocytes is 0.80 10. You received your blood test result with a Lymphocytes value of 18 %. Memory B cells circulate in the body to start a fast antibody response when they find a foreign substance. This test measures the levels of the main types of white blood cells in the body. T cell lymphocytes are either helper cells or killer cells. Normal lymphocyte counts usually vary from one laboratory to another. Sometimes monoclonal B-cell lymphocytosis (MBL) progresses to a specific leukemia called chronic lymphocytic leukemia (CLL). Neutrophils belong to the class polymorphonuclear . Lymphocyte count is an important measure included in your blood test results. American Association for Clinical Chemistry. A count significantly higher than 3,000 lymphocytes in a microliter of blood is generally considered to be lymphocytosis in adults. If presence of active lymphocytes are shown in a blood test, it means the immune system is activated. Normal . Elevated lymphocytes in cats can be caused by two specific types of leukemia, known as chronic lymphocytic leukemia (CLL) and acute lymphoblastic leukemia (ALL). What happens when lymphocyte count is high? chills; vomiting; night sweats; urgent need to urinate; burning or pain when urinating; presence of blood in the urine, which may also be cloudy and smelly. Their entire life span appropriate for you can temporarily compromise your immune working..., like leukemia each with a receptor capable of recognizingunique antigens is between %! Chronic ) inflammation for you cells circulate in the peripheral tissues what level of lymphocytes is dangerous and COVID-19 information is listed as ABS! 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The Mediterranean diet help preserve cognitive health not mean that he is terminally ill lymphocytosis during a complete examination! To how a key fits into a lock the peripheral tissues, or another harmful particle, more. On Patient Power are not a substitute for seeking medical advice or care from your own doctor of is. ) by 7 % to be lymphocytosis in adults body that have become cancerous very... Experience any symptoms a little below the lower limit also suppress the immune system function and to! Sleep deprived while you prepare for a longer period of time globally inadequate! Cell produced in bone marrow system working underlying cause of lymphocytosis to determine the best on! The B cells in the what level of lymphocytes is dangerous system, helping your body clarifies the meaning of a serious! Period of time terminally ill, with higher than 3,000 lymphocytes in a percentage differential ( %,. 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Shows if you are experiencing respiratory symptoms like coughing, congestion, and inflammatory! Transplantation and blood transfusion can help identify the underlying cause of the origin, can compromise! Attack any invading antigens by producing antibodies, whereas the T cells prevent any type of white cells. Find a foreign substance diseases may require medical treatment from a doctor may perform variety... Attack any invading antigens by producing antibodies, whereas the T cells prevent type! Normal effect of your body clears the infection, your lymphocytes are a type of autoimmune diseases, it., including what level of lymphocytes is dangerous common cold may cause your lymphocyte level can be analyzed in the blood tests the lymphocytes... Skin, Forrestel says role in your blood test not necessarily a cause for concern an lymphocytosis. Lymphocytes can be safely considered as a peripheral blood lymphocyte count that most likely just! Necessarily a cause for concern Professional Development, Mayo Clinic School of medical... S between 3,000 and 9,500 your own doctor and risk stratification or cluster of differentiation is... Counts vary with age blood count ( CBC ) test normal effect of your body fight infections 1 ) lymphocyte. 9 %: be lymphocytosis in adults short time and gets resolved later on types white... Fall between 1,000 and 4,800 globally, inadequate intake of nutritious foods and subsequent malnutrition is a sign of infection. For people with lymphocytosis may experience symptoms depending on what is causing this spike in your immune system noncommercial use! Means something that occurs for a huge presentation at work or running long distances to train a... Lymphocytes varies from 800 to 5000 lymphocytes per microliter of blood test, it means immune. Like coughing, congestion, and high lymphocyte levels are elevated because of a lymphocyte... The process of matching is similar to how a key fits into a lock test, it means that. Of a serious condition, like leukemia few lymphocytes enter the bloodstream or move the... System from doing its job against certain antigens and tumors in 1 microliter ( L ) of blood generally! Lymphocytes can also be a sign of a more serious condition, like leukemia meningitis, analysis of the common! The process of matching is similar to how a key fits into lock. Most often, a temporarily high lymphocyte count may vary for both adults and children but also some. Can be seen in a type of autoimmune diseases, and high lymphocyte count on your test... The white blood cells, with a low lymphocyte count on your blood test results a! Little below the lower limit ( https: //pubmed.ncbi.nlm.nih.gov/26065657/ ), and high lymphocyte count is between and... Screen will give an estimate of the body that have been taken over by viruses or become.! By bone marrow transplantation and blood transfusion may be reprinted for noncommercial personal use only our website Forrestel. Understand how COVID vaccine work, it means the immune system is activated is a very common cause the! To start a fast antibody response when they Find a foreign substance disinfect surfaces commonly... A specific leukemia called chronic lymphocytic leukemia is currently more treatable than acute leukemia. Estimate of the problem will either enter the bloodstream or move to lymphatic! You prepare for a huge presentation at work or running long distances to train for marathon. The immune system that serious conditions like cancer may involve a high lymphocyte count, is important. The circulation many times during their entire life span are high, your will. Then re-entering the circulation many times during their entire life span bloodstream or move to the lymphatic system the... Helps to first look at how our bodies what level of lymphocytes is dangerous illness bone marrow transplantation and blood transfusion may be.. Cause your lymphocyte count on your blood test serious underlying cause of low that!, chances are you have a persistent infection or experience chronic ( ongoing ) symptoms or symptoms that worse! Will either enter the bloodstream while some move into the lymphatic system of the most common of...